BDBM347812 US9790221, Compound 18

SMILES COC(=O)c1nnc(s1)-c1cnc(nc1NC1CCCNC1)-c1cccc(c1)-c1cnn(C)c1

InChI Key InChIKey=IWLJECYMUNPASG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 347812   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM347812(US9790221, Compound 18)
Affinity DataIC50: <100nMAssay Description:IRAK4 is a human purified recombinant enzyme (His-TEV-IRAK1 (194-712). IRAK4 hydrolyses ATP, autophosphorylates and phosphorylates a Serine/Threonine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent